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Hardcover Comprehensive Toxicology, Volume 10: Reproductive and Endocrine Toxicology Book

ISBN: 0080429750

ISBN13: 9780080429755

Comprehensive Toxicology, Volume 10: Reproductive and Endocrine Toxicology

Hardbound. Section 1, the section on male reproductive toxicology, starts with a basic overview on the anatomy and physiology of the system. This is followed by reviews on the way molecules are evaluated for male reproductive toxicity in both the pharmaceutical and chemical industries, along with a strategy for evaluating the reproductive function of transgenic animals. The bulk of this section is devoted to reviewing mechanisms and manifestations of toxicants to particular targets within the male reproductive system (Sertoli cell, Leydig cell, etc.). Finally, a significant part evaluates areas of interest not often considered in the toxicologic context (fluid flow, the immune system, paracrine factors, etc.), as well as a part highlighting technical advances and what these mean for the field. Overall, this volume reviews the state of the science in a number of areas, explicitly provides strategies for investigators to use in addressing their own probl

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