Formulation evaluation of bilayer tablet of saxagliptin & repaglinide
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Bilayer tablet has been made and evaluated. For various precompression and post compression parameter. Precompression parameter shows that the granules and blends of repaglinide and saxagliptin have good Carr's index and hausner's ratio indicate that both granules and blends were free flowing. The angle of repose shows that granules and blends have excellent flow and post compression parameter show that bilayer tablet have thickness hardness and weight and friability within the I. P. limit and bilayer tablet have swelling index 82% in 6 hrs and have drug release first layer of saxagliptin release 98.6% in 30 minutes and second layer repaglinide release 95.5% in 12 hrs.
Format:Paperback
Language:English
ISBN:6206144445
ISBN13:9786206144441
Release Date:February 2023
Publisher:LAP Lambert Academic Publishing
Length:96 Pages
Weight:0.33 lbs.
Dimensions:0.2" x 6.0" x 9.0"
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