Glaucoma: Methods and Protocols

1. Use of Animal Models and Techniques in Glaucoma Research: Introduction

Harry A. Quigley

2. Hypertonic Saline Injection Model of Experimental Glaucoma in Rats

John C. Morrison, Elaine C. Johnson, and William O. Cepurna

3. The Microbead Occlusion Model of Ocular Hypertension in Mice

David J. Calkins, Wendi S. Lambert, Cathryn R. Formichella, William M. McLaughlin, and Rebecca M. Sappington

4. Ocular Hypertension/Glaucoma in Minipigs: Episcleral Veins Cauterization and Microbead Occlusion Methods

Elena Vecino, Haritz Urcola, and Sansar C. Sharma

5. Non-Invasive Intraocular Pressure Measurement in Animals Models of Glaucoma

Yan Hu and John Danias

6. High Throughput Binocular Pattern Electroretinograms in the Mouse

Tsung-Han Chou, Jonathon Toft-Nielsen, and Vittorio Porciatti

7. Visual Evoked Potentials in Glaucoma and Alzheimer's Disease

Elisa Cerri, Carlotta Fabiani, Chiara Criscuolo, and Luciano Domenici

8. Investigation of the Functional Retinal Output Using Microelectrode Arrays

9. Quantitative Proteomic Analysis of Human Aqueous Humor Using iTRAQ 4plex Labeling

Anna Trzeciecka, Padmanabhan Pattabiraman, Maria Carmen Piqueras, Carol Toris, and Sanjoy K. Bhattacharya

10. Sphingolipid Analysis of Aqueous Humor

Anna Trzeciecka, Arturo Barron, Genea Edwards, Sruthi Sampathkumar, Carol Toris, and Sanjoy K. Bhattacharya

11. Assessment of Aqueous Humor Dynamics in the Rodent by Constant Flow Infusion

J. Cameron Millar, Tien N. Phan, and Iok-Hou Pang

12. Methods for Analyzing Endoplasmic Reticulum Stress in the Trabecular Meshwork of Glaucoma Models

Prabhavathi Maddineni, Ramesh B. Kasetti, and Gulab S. Zode

13. Quantification of Scleral Biomechanics and Collagen Fiber Alignment

14. Biolistic Labeling of Retinal Ganglion Cells

Luca Della Santina and Yvonne Ou

15. Anterograde Tract Tracing for Assaying Axonopathy and Transport Deficits in Glaucoma

Samuel D. Crish and Brett R. Schofield

16. In Vitro and In Vivo Methods for Studying Retinal Ganglion Cell Survival and Optic Nerve Regeneration

17. 3D Histomorphometric Reconstruction and Quantification of the Optic Nerve Head Connective Tissues

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