High-Throughput Metabolomics: Methods and Protocols
(Book #1978 in the Methods in Molecular Biology Series)
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Book Overview
This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about thenext generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.
Format:Hardcover
Language:English
ISBN:149399235X
ISBN13:9781493992355
Release Date:May 2019
Publisher:Humana
Length:459 Pages
Weight:2.20 lbs.
Dimensions:1.1" x 7.2" x 10.2"
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