Over fifty million people suffer from some form of autoimmune disease-multiple sclerosis, arthritis, lupus, and other afflictions in which the body attacks itself-none of them with a lasting cure. Susan Quinn has investigated the worlds where new autoimmune drugs are being developed: the research labs, the drug-company boardrooms, and the clinics where patients become "subjects" in the search for new medicines and treatments. Her exciting story is one of real people: fiercely competing scientists, ambitious venture capitalists, and, above all, anxious, sick human beings. She takes the reader inside these otherwise closed worlds, into the lead investigator's diaries, the tense closed-door meetings with investors, and the hopeful or heart-rending encounters in doctor's offices. Hers is the archetypal story of all medical research: the roller-coaster trip from the lab bench to the medicine cabinet, in which only a very few new drugs and treatments survive. Susan Quinn, author of the acclaimed biography Marie Curie, catches the hopes, triumphs, and crushing failures, the greed and the idealism in these dramatic human trials.
Susan Quinn's Human Trails blends science with medical insights as it draws unusual and important connections between scientists, investors in scientific and medical research, and how drug trials are financed and conducted. Hers is written from lead investigator diaries and closed-door meetings with investors, offering more than an outside look at the facts.
A Thrilling Journey into the War Against Disease
Published by Thriftbooks.com User , 23 years ago
I knew Susan Quinn's HUMAN TRIALS would be an engaging, informative inquiry into the intricate process of bringing a new drug therapy to market. What I didn't expect was that the book would read like the best of thrillers -- it takes the reader on the suspenseful and sometimes heart-wrenching journey into the very heart of the war against disease. HUMAN TRIALS is ultimately about the people who populate the closed society that chronic, degenerative illness creates (in this case, MS and rheumatoid arthritis): the patients and their families who suffer and hope, and the doctors, scientists, and investors who, from motives that mix intellectual egotism, financial gain, and selfless dedication, bring their best weapons of mind and spirit to the battle. Quinn does an admirable job describing and demystifying the strategy involved in one novel approach to conquering, or at least containing, MS and RA; the reader learns in compelling detail just what it takes to develop an untested theory into a viable, marketable protocol. However, HUMAN TRIALS goes beyond scientific process to tell a story of risk and courage on both sides of the line. On this particular journey, failure is simply a subset of perseverance, knowledge arrives in unexpected ways, and victory is really a matter of the heart more than the body.
Facinating look into clinical trials
Published by Thriftbooks.com User , 23 years ago
This book grabbed me from the start since I also have one of those incurable, untreatable autoimmune diseases that rarely threaten your life, but certainly ruin it. Scleroderma patients had a recent, similar roller-coaster ride with what was thought to be a promising therapy. I could easily relate to everyone involved - patients, treating doctors, researchers, and investors. Ms Quinn took very complex material about MS and the research surrounding it and made it understandable, while telling an exciting and emotionally engaging story. Though it doesn't help me to cope day-to-day with my disease, it does make me understand the processes and people involved in the search for a treatment.
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