Chemical Genomics and Proteomics: Reviews and Protocols

Part I: Reviews

1. Overview of Chemical Genomics and Proteomics

Edward D. Zanders

2. Exploring Chemical Space: Recent Advances in Chemistry

Yung-Sing Wong

3. In Silico Design of Small Molecules

Paul H. Bernardo and Joo Chuan Tong

4. Surface Plasmon Resonance for Proteomics

Nico J. de Mol

Part II: Protocols

5. Biomimetic Affinity Ligands for Immunoglobulins Based on the Multicomponent Ugi Reaction

Graziella El Khoury, Laura A. Rowe, and Christopher R. Lowe

6. Preparation of Photo-Cross-Linked Small Molecule Affinity Matrices for Affinity Selection of Protein Targets for Biologically Active Small Molecules

Hiroshi Takayama, Takashi Moriya, and Naoki Kanoh

7. Profiling Cellular Myristoylation and Palmitoylation Using ω-Alkynyl Fatty Acids

Rami N. Hannoush

8. Fluorescence Labels in Kinases (FLiK): A High-Throughput Kinase Binding Assay for the Identification of DFG-Out Binding Ligands

Jeffrey R. Simard and Daniel Rauh

9. Electrochemical Aptamer Sensor for Small Molecule Assays

Xin Liu, Wang Li, Xiahong Xu, Jiang Zhou, and Zhou Nie

10. Miniaturized, Microarray-Based Assays for Chemical Proteomic Studies of Protein Function

Jonathan M. Blackburn, Aubrey Shoko, and Natasha Beeton-Kempen

11. Glycan Microarrays

Xuezheng Song, Jamie Heimburg-Molinaro, David F. Smith, and Richard D. Cummings

12. Resolving Bottlenecks for Recombinant Protein Expression in E. coli

Yoav Peleg and Tamar Unger

13. Recombinant Protein Expression in the Baculovirus-Infected Insect Cell System

Tamar Unger and Yoav Peleg

14. Systems for the Cell-Free Synthesis of Proteins

Lei Kai, Christian Roos, Stefan Haberstock, Davide Proverbio, Yi Ma, Friederike Junge, Mikhail Karbyshev, Zhinan Xu, Volker D?tsch, and Frank Bernhard

15. Protein Identification by MALDI-TOF Mass Spectrometry

Judith Webster and David Oxley