Ocular Photodynamic Therapy

Ocular Photodynamic Therapy provides a comprehensive overview of this innovative treatment modality that has changed the current approach to this condition. Important topics are reviewed including the natural history of choroidal neovascularization (CNV), conventional laser photocoagulation, and surgical management of neovascular complexes. Key studies validating photodynamic therapy (PDT) are covered in detail including the Treatment of Age-related Macular Degeneration with Photodynamic Therapy (TAP) and Verteporfin in Photodynamic Therapy (VIP) trials. The principles of PDT are outlined including photosensitizers and photoactivation. The procedure protocol is described step-by-step covering patient selection, drug preparation, and treatment parameters. The treatment procedure is described along with recommendations for follow-up and retreatment. Practical examples are given to underscore the indications, limitations, potential pitfalls, and complications encountered with this new procedure. Expanded indications are discussed to assist in the potential treatment of lesions that do not meet strict study inclusion criteria. The book is extensively illustrated with representative color photographs, fluorescein angiograms, and optical coherence tomograms. The beginning PDT practitioner will appreciate the straightforward instructions and explanations. More experienced individuals will benefit from the authors' insights into the finer points encountered in using this new modality.