The laboratory rat remains the most widely used species for the testing of potentially carcinogenic agents in vivo, and reliable information on the classification and nature of spontaneous and induced tumors in this species is essential. Thoroughly up-to-date, this edition has been largely rewritten and several new chapters have been added. Each chapter deals with a particular organ or tissue, describing normal structure, the morphology and biology of tumors (including the histological classification), spontaneous tumors, induction, non-neoplastic lesions, and comparative aspects. Many pages of photomicrographs help clarify the material presented in the text.
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